abstract：:Dual-drug delivery systems were constructed through coaxial techniques, which were convenient for the model drugs used the present work. This study aimed to fabricate core-shell electrospun nanofibrous membranes displaying simultaneous cell proliferation and antibacterial activity. For that purpose, phenytoin (Ph), a ...

authors： Mohamady Hussein MA,Guler E,Rayaman E,Cam ME,Sahin A,Grinholc M,Sezgin Mansuroglu D,Sahin YM,Gunduz O,Muhammed M,El-Sherbiny IM,Megahed M

更新日期：2021-10-15 00:00:00

abstract：:Rapid and effective hemorrhage control is essential to reduce mortality following traumatic injuries. Herein we developed an organic solvent-free process to prepare carboxymethyl chitin microsphere (CMCHm) in an aqueous two-phase system through heating and freeze-drying. To further enhance the hemostatic performance o...

authors： Leng F,Chen F,Jiang X

更新日期：2021-10-15 00:00:00

abstract：:In this research, the polypyrrole/silver (PPy/Ag) composite was first in-situ prepared on alginate fabrics by chemical oxidative polymerization of pyrrole (Py) monomer using silver nitrate as oxidant and sodium dodecyl sulfate (SDS) as the dopant. The effects of mole ratio of Py to silver nitrate, reaction time and do...

authors： Ji F,Guo X,Liu A,Xu P,Tan Y,Wang R,Hao L

更新日期：2021-10-15 00:00:00

abstract：:Cellulose, as the most abundant natural polysaccharide, is an excellent material for developing green humidity sensors, especially due to its humidity responsiveness as a result of its rich hydrophilic groups. In combination with other components including carbon materials and polymers, cellulose and its derivatives c...

authors： Li Z,Wang J,Xu Y,Shen M,Duan C,Dai L,Ni Y

更新日期：2021-10-15 00:00:00

abstract：:Adsorbent materials based on titania and phosphate are ideal for treatment of solutions contaminated with heavy metals under acidic conditions, due to their inherent chemical stability and low pKa. Herein, phosphate functionalised titania has been investigated for the first time for removal of heavy metals (Cr, Fe, Cu...

authors： Hallam L,Papasergio AE,Lessio M,Veliscek-Carolan J

更新日期：2021-10-15 00:00:00

abstract：:Two-dimensional photocatalytic materials have attracted great attention due to their large specific surface area and abundant active sites. Suppressing the recombination of photo-excited carriers is an effective approach to improve the performances of photocatalytic materials. Herein, we introduced ferroelectric PbTiO...

authors： Zheng M,Xu Q,Tian R,Lu C

更新日期：2021-10-15 00:00:00

abstract：:A modified QuEChERS method for determining cyenopyrafen in strawberries, mandarins and their processed products was established with a good linearity (R2 > 0.9981), accuracy (recoveries of 83% to 111%) and precision (relative standard deviations of 0.9% to 14%). The limit of quantification (LOQ) was 0.01 mg/kg. Field ...

authors： Li Y,Xu J,Zhao X,He H,Zhang C,Zhang Z

更新日期：2021-10-15 00:00:00

abstract：:A validated method for B vitamin separation and quantification from lentil seeds using ultra high performance liquid chromatography-selected reaction monitoring mass spectrometry (UHPLC-SRM MS) was reported. The use of three enzymes (acid phosphatase, β-glucosidase, and rat serum) with a 4 h incubation was sufficient ...

authors： Zhang H,De Silva D,Dissanayaka D,Warkentin TD,Vandenberg A

更新日期：2021-10-15 00:00:00

abstract：:Synchrony can be defined as the precise coordination between independent individuals, and this behaviour is more enigmatic when it is imperfect. The traditional theoretical explanation for imperfect synchronous courtship is that it arises as a by-product of the competition between males to broadcast leading signals to...

authors： Perez DM,Klunk CL,Araujo SBL

更新日期：2021-10-11 00:00:00

abstract：:Rhythms are important for understanding coordinated behaviours in ecological systems. The repetitive nature of rhythms affords prediction, planning of movements and coordination of processes within and between individuals. A major challenge is to understand complex forms of coordination when they differ from complete ...

authors： Dotov D,Trainor LJ

更新日期：2021-10-11 00:00:00

abstract：:The productive sector must incorporate waste into traditional materials in order to grow sustainably. In Galicia (Spain) alone, the canning industry produces over 150,000 metric tons of seashell waste per year. Most of this waste is still disposed of in landfills or open fields due to the lack of a technically feasibl...

authors： Peceño B,Alonso-Fariñas B,Vilches LF,Leiva C

更新日期：2021-10-10 00:00:00

abstract：:The ecological consequences of soil salinization, one of the major causes of soil degradation worldwide, on soil carbon (C) emissions are well known, but less is known about the related microbial C metabolic function. We conducted laboratory incubation experiments on soil samples under a salt gradient at four levels (...

authors： Yang C,Lv D,Jiang S,Lin H,Sun J,Li K,Sun J

更新日期：2021-10-10 00:00:00

abstract：:It is often challenging to design diagnostic and therapeutic agents that fulfill all functional requirements. So, bulk and surface modifications as a common approach for biomedical applications have been suggested. There have been considerable research interests in using nanomaterials to the prementioned methods. Amon...

authors： Delyanee M,Akbari S,Solouk A

更新日期：2021-10-05 00:00:00

abstract：:Long-term survivors of glioblastoma multiforme (GBM) are at high risk of developing second primary neoplasms, including leukemia. For these patients, the use of classic tyrosine kinase inhibitors (TKIs), such as imatinib mesylate, is strongly discouraged, since this treatment causes a tremendous increase of tumor and ...

authors： Puxeddu M,Shen H,Bai R,Coluccia A,Bufano M,Nalli M,Sebastiani J,Brancaccio D,Da Pozzo E,Tremolanti C,Martini C,Orlando V,Biagioni S,Sinicropi MS,Ceramella J,Iacopetta D,Coluccia AML,Hamel E,Liu T,Silvestri R,La Re

更新日期：2021-10-05 00:00:00

abstract：:Hydroxypyranone and hydroxypyridinone are important oxygen-containing or nitrogen-containing heterocyclic nucleus and attracted increasing attention in medicinal chemistry and drug discovery over the past decade. Previous literature reports revealed that hydroxypyranone and hydroxypyridinone derivatives exhibit a wide...

authors： He M,Fan M,Peng Z,Wang G

更新日期：2021-10-05 00:00:00

abstract：:Natural peptides extracted from natural components such are known to have a relatively short in-vivo half-life and can readily metabolize by endo- and exo-peptidases. Fortunately, synthetic peptides can be easily manipulated to increase in-vivo stability, membrane permeability and target specificity with some well-kno...

authors： Askari Rizvi SF,Zhang H

更新日期：2021-10-05 00:00:00

abstract：:Invasive fungal infections remain a challenge due to lack of effective antifungal agents and serious drug resistance. Discovery of antifungal agents with novel antifungal mechanism is important and urgent. Previously, we designed the first CYP51/HDAC dual inhibitors with potent activity against resistant Candida albic...

authors： Zhu T,Chen X,Li C,Tu J,Liu N,Xu D,Sheng C

更新日期：2021-10-05 00:00:00

abstract：:In this work novel antiviral compound 4-(Dimethylamino) Pyridinium 3, 5-dichlorosalicylate was synthesized and characterized by UV-vis, FT-IR, FT-Raman, 1H NMR and 13C NMR spectra. Quantum chemical computations were carried out by Density functional theory methods at B3LYP level. Electronic stability of the compound a...

authors： Tarika JDD,Dexlin XDD,Madhankumar S,Jayanthi DD,Beaula TJ

更新日期：2021-10-05 00:00:00

abstract：:The determination of the abundances of the CHx, C = O and aromatic groups in chondritic Insoluble Organic Matter (IOM) and coals by Infrared (IR) spectroscopy is a challenging issue due to insufficient knowledge on the absorption cross-sections and their sensitivity to the molecular environment. Here, we report a cali...

authors： Phan VTH,Quirico E,Beck P,Le Brech Y,Jovanovic L,Le Guillou C,Bernard S,Bonal L,Carrasco N,Gautier T,Raya J

更新日期：2021-10-05 00:00:00

abstract：:Paclitaxel is the best natural anticancer drug and artemisinin also has anticancer effect. In this study, the interactions between BSA and these two drugs were determined in PBS (pH 7.40) by multi-spectroscopic method and molecular dynamics (MD) simulations. The results showed that paclitaxel and artemisinin could sta...

authors： Qi H,Wang Y,Wang X,Su L,Wang Y,Wang S

更新日期：2021-10-05 00:00:00

abstract：:Symbiotic autonomous systems (SAS) are advanced intelligent and cognitive systems that exhibit autonomous collective intelligence enabled by coherent symbiosis of human-machine interactions in hybrid societies. Basic research in the emerging field of SAS has triggered advanced general-AI technologies that either funct...

authors： Wang Y,Karray F,Kwong S,Plataniotis KN,Leung H,Hou M,Tunstel E,Rudas IJ,Trajkovic L,Kaynak O,Kacprzyk J,Zhou M,Smith MH,Chen P,Patel S

更新日期：2021-10-04 00:00:00

abstract：:Membrane traffic is an important regulator of cell migration through the endocytosis and recycling of cell surface receptors such as integrin heterodimers. Intracellular nanovesicles (INVs) are transport vesicles that are involved in multiple membrane trafficking steps, including the recycling pathway. The only known ...

authors： Larocque G,Moore DJ,Sittewelle M,Kuey C,Hetmanski JHR,La-Borde PJ,Wilson BJ,Clarke NI,Caswell PT,Royle SJ

更新日期：2021-10-04 00:00:00

abstract：:Chronic stress is a relevant disease to periodontal practice, encompassing 25%-28% of the US population (American Psychological Association 2015). While it is well established that chronic psychologic stress can have significant deleterious systemic effects, only in recent decades have we begun to explore the biochemi...

authors： Decker AM,Kapila YL,Wang HL

更新日期：2021-10-01 00:00:00

abstract：:Gastric cancer (GC) is one of the main causes of cancer-associated morbidity and mortality worldwide. The present study aimed to investigate the role of the gene encoding formin homology 2 domain containing 1 (FHOD1) protein in GC development. Data from The Cancer Genome Atlas were firstly analyzed, and immunohistoche...

authors： Jiang C,Yuan B,Hang B,Mao JH,Zou X,Wang P

更新日期：2021-10-01 00:00:00

abstract：:Mucoepidermoid carcinoma (MEC) is one of the most frequently misdiagnosed tumors. Glycans are modulated by malignant transformation. Mucin 1 (MUC1) is a mucin whose expression is upregulated in various tumors, including MEC, and it has previously been investigated as a diagnostic and prognostic tumor marker. The prese...

authors： Isaka E,Sugiura T,Hashimoto K,Kikuta K,Anazawa U,Nomura T,Kameyama A

更新日期：2021-10-01 00:00:00

abstract：Objectives:To determine optimal handgrip strength (HGS) cutoff points for greater functional independence and wheelchair skills in men with spinal cord injury (SCI), and to establish predictive equations for functional independence and wheelchair ability in men with SCI, based on demographic characteristics, HGS, and f...

authors： Neto FR,Gomes Costa RR,Dorneles JR,Gonçalves CW,Veloso JHCL,Carregaro RL

更新日期：2021-10-01 00:00:00

abstract：:Hypoxia is involved in the epigenetic modification of leukemia. As an important DNA hydroxymethylase and a tumor suppressor gene, the expression regulating mechanism of Tet methylcytosine dioxygenase 2 (TET2) remains unclear. The aim of the present study was to explore whether hypoxia and hypoxia-inducible factor 1α (...

authors： He P,Lei J,Zou LX,Zhou GZ,Peng L,Deng Q,Liu XL

更新日期：2021-10-01 00:00:00

abstract：:Obesity is a pandemic and periodontitis is the sixth most prevalent disease in the world. These two noncommunicable diseases share several risk determinants. Epidemiologic evidence from the last 2 decades has established an increase in periodontitis prevalence in obese and overweight individuals. Biologic mechanisms p...

authors： Ganesan SM,Vazana S,Stuhr S

更新日期：2021-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Literature on the use of current magnetic resonance imaging (MRI) for patients with idiopathic sudden sensorineural hearing loss (ISSNHL) is reviewed, emphasizing the role of three-dimensional fluid-attenuated inversion recovery (3D-FLAIR) MRI. The discussion focuses on the diagnostic role of temporal...

authors： Yoon RG,Choi Y,Park HJ

更新日期：2021-10-01 00:00:00

abstract：:Human papillomavirus-associated oropharyngeal cancer (HPV-OPC) is a distinct clinical entity with a favorable prognosis compared with non-HPV-OPC. Surgery and radiotherapy (RT) result in adverse effects, and negative quality of life or functional outcomes, which impact a significant proportion of HPV-OPC survivors. On...

authors： Dagan R,Galloway TJ

更新日期：2021-10-01 00:00:00

abstract：:Conventional factor analyses can present problems in cases with changing numbers of sources and/or time-dependent source compositions. There is also lack of a reliable method to estimate uncertainties in the source contributions derived by positive matrix factorization (PMF). Applying a moving window evolving PMF to h...

authors： Song L,Dai Q,Feng Y,Hopke PK

更新日期：2021-10-01 00:00:00

abstract：:Periodontitis is a common chronic inflammatory disease characterized by destruction of the supporting structures of the teeth. Severe periodontitis is highly prevalent-affecting 10%-15% of adults-and carries several negative comorbidities, thus reducing quality of life. Although a clear relationship exists between sev...

authors： Kwack KH,Maglaras V,Thiyagarajan R,Zhang L,Kirkwood KL

更新日期：2021-10-01 00:00:00

abstract：:Transformation products (TPs) of micropollutants contaminating our water resources have become an emerging issue due to the potential threats they pose to environmental and human health. This study investigated the transformation chemistry, toxicity, physicochemical properties and environmental behavior resulting from...

authors： Law JC,Huang Y,Chow CH,Lam TK,Leung KS

更新日期：2021-10-01 00:00:00

abstract：:The temporomandibular joint (TMJ), the most complex and evolved joint in humans, presents two articular surfaces: the condyle of the mandible and the articular eminence (AE) of the temporal bone. AE is the anterior root of the zygomatic process of the temporal bone and has an anterior and a posterior slope, the latter...

authors： Vîrlan MJR,Păun DL,Bordea EN,Pellegrini A,Spînu AD,Ivașcu RV,Nimigean V,Nimigean VR

更新日期：2021-10-01 00:00:00

abstract：:We assessed the contribution of transboundary air pollutants (TAPs) transported from China to Tokyo using the Pb(0.5 journal_title：Environmental pollution (Barking, Essex : 1987)

authors： Shimada K,Mizukoshi M,Chan CK,Kim YP,Lin NH,Matsuda K,Itahashi S,Nakashima Y,Kato S,Hatakeyama S

更新日期：2021-10-01 00:00:00

abstract：:Rheumatoid arthritis (RA), a chronic inflammatory synovitis systemic disease, can lead to joint deformities, loss of function and even death. The pathogenesis of RA may be related to genetics, infection and/or sex hormones; however, detailed accounts of the molecular mechanisms underlying its pathogenesis are lacking....

authors： Li Y,Qi W,Yan L,Wang M,Zhao L

更新日期：2021-10-01 00:00:00

abstract：:The role of GAS6 antisense RNA 1 (GAS6-AS1) in clear cell renal cell carcinoma (ccRCC) remains unclear. The aim of the present study was to investigate the role and molecular mechanisms of GAS6-AS1 in the progression of ccRCC. GAS6-AS1 was found to be upregulated in ccRCC tissues and cell lines, and patients with high...

authors： Guo X,Li H,Zhang M,Li R

更新日期：2021-10-01 00:00:00

abstract：SUMMARY:Fighting the global COVID-19 pandemic has shifted from immediate response efforts to recognition of the long-term effects on the mental health and well-being of the general population and healthcare workforce. Leaders need to understand the vital role of behavioral health services in a population-based, integra...

authors： Merz SM

更新日期：2021-10-01 00:00:00

abstract：:Parkinson's disease (PD) is the second most common neurodegenerative disease amongst the middle‑aged and elderly populations. Several studies have confirmed that the microbiota‑gut‑brain axis (MGBA) serves a key role in the pathogenesis of PD. Changes to the gastrointestinal microbiome (GM) cause misfolding and abnorm...

authors： Lei Q,Wu T,Wu J,Hu X,Guan Y,Wang Y,Yan J,Shi G

更新日期：2021-10-01 00:00:00

abstract：:The conventional storage temperature of 16-18 °C provides optimal conditions for the preservation of boar sperm quality, which are extremely cold sensitive cells. On the other hand, however, it requires the addition of antibiotics to inhibit bacterial growth. Rising numbers of antibiotic resistant bacteria call for al...

authors： Jakop U,Hensel B,Orquera S,Rößner A,Alter T,Schröter F,Grossfeld R,Jung M,Simmet C,Schulze M

更新日期：2021-10-01 00:00:00